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June 24, 2016: Possible Kidney Disease Heart Burn Medication Association

Kidney Disease Heart Burn Medication

Medications such as Nexium, Prevacid, and Prilosec have been linked to kidney health issues, such as chronic kidney disease. These medications, also known as Proton Pump Inhibitor (PPI) medications, are used to control stomach acid and manage symptoms of heart burn, acid reflux, and indigestion.

Potential Danger of Kidney Failure

This increased risk of developing chronic kidney disease in those taking PPIs has been supported by several studies. Most recently, a study published in February 2016 in the Journal of the American Medical Association found that PPIs may increase the chance of suffering from chronic kidney disease as much as 50%.

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Chronic Kidney Disease

ucm251847The main job of the kidneys is to remove wastes and excess water from the body. Chronic kidney disease is the slow loss of kidney function over time. Signs and symptoms of kidney disease may include, among others:

  • Nausea
  • Vomiting
  • Fatigue and weakness
  • Changes in urine output
  • Decreased mental sharpness
  • Muscle twitches and cramps
  • Swelling of feet and ankles
  • Persistent itching
  • Chest pain, if fluid builds up around the lining of the heart
  • Shortness of breath, if fluid builds up in the lungs
  • High blood pressure (hypertension) that’s difficult to control

Additional Risks

PPI medication use puts patients at risk for a variety of serious complications in addition to chronic kidney disease and heart attack, including:

    • Hypomagnesemia
    • Bone Fractures
    • Acquired Infections
    • Potential Birth Defects

PPIs may also increase the risk of various kidney events, including acute kidney injury and an inflammatory Kidney disease known as acute interstitial nephritis.

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